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The chronicity and risk for relapse with the need for lifelong sun protection should be emphasised to set realistic goals and outcomes

It has broader effects on metabolism, body composition, and recovery beyond just healing

Furthermore, it has been shown that endothelin-1 and VEGF, which are responsible for enhanced vascularity in melasma lesions, can be diminished by tranexamic acid administration

Early phagocytosis of glucose-6-phosphate dehydrogenase (G6PD)-deficient erythrocytes parasitized by Plasmodium falciparum may explain malaria protection in G6PD deficiency

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PMCID: PMC8505337