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These are not theoretical risks

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How to read preclinical evidence without over-reading it Preclinical does not mean worthless it means early

Although the magnitude of the A 1c change is small, it is consistent with the expectations for antidiabetic agents administered to subjects having excellent baseline control, and is similar to what has been observed in previous clinical trials evaluating antidiabetic agents (39)

Metformin, commonly prescribed for type 2 diabetes, is well-known to cause diarrhoea and is also associated with B12 deficiencymeaning patients may be taking both simultaneously

It is dosed at 200 mcg to 500 mcg daily, subcutaneously typically at night to align with the bodys natural GH pulse