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While reassuring, a 2-person study cannot establish safetysystematic surveillance in larger populations has not been conducted
The PDO in humans is a single-domain enzyme, while bacterial PDOs, such as CstB of Staphylococcus aureus , are often fused to a sulfurtransferase (rhodanese) module
In addition, patients aged 64 years old or older with rheumatoid arthritis and heart failure show an increased risk of hospitalization due to heart failure, so this medication is only recommended for patients with compensated heart failure if there are no other reasonable treatment options
Exposure to NPs through inhalation or systemic administration can cause NPs accumulation in organs such as the lungs, liver, or kidneys with inflammation or neurotoxicity (27)
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