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Finally, various concentrations of inhibitor were mixed with 1.2 mM L-tyrosine or 2 mM L-dopa and were added to the pre-incubated mixture

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Then, they get regular doses to keep levels right

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Fogelman DR, Wolff RA, Kopetz ES , Javle M, Bradley C, Mok I, Cabanillas F, Abbruzzese JL