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Optimization and Plateau Considerations (Weeks 12-16+): After 12-16 weeks of use, the rate of body composition change may slow as users approach their genetic set points or as the body adapts metabolically

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[19] The onset may be vague and slow and the condition can be confused with other conditions, and there may be few to many symptoms without anemia

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its strongest evidence base is in cardiac muscle, skeletal muscle, and skin wound healing models The combination is studied to investigate whether the two pathways exhibit additive or synergistic effects across tissue repair endpoints a question that would be difficult to study with either compound alone

doi:10.1146/annurev.nutr.19.1.357