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Levels 300-400 ng/mL typical therapeutic targets though individual variation

This makes them suitable for a proof-of-concept trial: there is real variation to detect, and a real-world population that would benefit from better intervention options

Cocci, A., Russo, G

Cell-binding peptides PepGen P-15 The P-15 peptide is a highly conserved peptide that consists of 15 amino acids identical to the cell-binding region of collagen type I [234]

Below that shared effect, the molecular stories diverge completely

The resulting inflammation contributes to the characteristic redness, swelling, and pustule formation associated with acne vulgaris