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The concept of trained immunity poses that long-term functional changes in innate immune cells can be induced by certain challenges, which are mediated by epigenetic reprogramming of innate immune cells and their stem/progenitor cells

Attempts to extrapolate our current limited knowledge of single field science into a clinical protocol without consideration of the multi-system involvement often fails and indeed frequently worsens this condition

About The Authors: Yashoda Sharma, Ph.D., is a program director at the Digital Medicine Society (DiMe), a 501(c)(3) nonprofit organization dedicated to advancing digital medicine to optimize human health