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It may have a slightly lower rate of serious infections compared to other biologic DMARDs (Schur & Cohen, 2014) twice weekly sc maintenance dosing due to its short half-life Adalimumab a recombinant 100% human IgG1 monoclonal antibody specific for TNF- similar efficacy as methotrexate (Schur & Cohen, 2014) can be given s.c

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Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3