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It should also be noted that significant quantities of O 2 - are produced in the reactions catalyzed by iNOS, and O 2 - reacts with NO to generate peroxynitrite (ONOO ) with strong oxidizing and nitriding properties (95)

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The first hitsuch as infection or toxin exposuremay establish a state of susceptibility, with exercise acting as the second hit that ignites the potential pathological cycle

However, in response to oxidative stress, GPX7 can promote stress signal transduction and release through interaction with corresponding targeted proteins

Monico, C

Knopf, D