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Deficiency is particularly common in elderly people, because the ability to absorb vitamin B12 can decrease with age

TRAP1 inhibits mitochondrial c-Src activity by binding to it and preventing its auto-activation by phosphorylation, thereby exerting some of its effects on mitochondrial respiration through this kinase [111]

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This does not mean peptides are useless

GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect

Furthermore, oxLDL induces the release of pro-inflammatory cytokines, perpetuating inflammation and promoting the progression of atherosclerotic plaques [73]