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Oxidative stress can Be attenuated by 4-PBA caused by high-fat or ammonia nitrogen in cultured spotted seabass: the mechanism is related to endoplasmic reticulum stress

These affects were BA-dependent because (1) depletion of the BA receptor FXR and (2) genetic deletion of a BA-metabolizing enzyme abrogated these affects (174)

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Specifically, glutathione plays an indispensable role in the innate immune response, the frontline defense against invading pathogens

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