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As a result, surface expression of B2M and class I HLAs is reduced, helping the virus evade identification and clearance of infected cells by cytotoxic CD8+ T cells (138, 158, 159)

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Patients with a personal or family history of cancer, those who are pregnant or breastfeeding, or those taking immunosuppressants should discuss individualized risk-benefit considerations with their provider

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The safety was preliminarily verified: The acute toxicity test showed that a single subcutaneous injection of AOD 9604 (50 mg/kg) did not cause death or obvious toxic reactions in mice

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