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ABAD directly links Abeta to mitochondrial toxicity in Alzheimers disease

Qin et al., 2012)

Alterations in methylation patterns are also a fundamental mechanism for epigenetic modifications, allowing for transgenerational effects

10.1155/2013/509130 Can Respir J

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Tip of the iceberg The tip of the metabolic iceberg conveys the clinical, anatomical, and pathological features for each neurodegenerative disorder, the most visible of which are the hallmark features