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Further studies are needed to investigate the issue

As with any growth-factor therapy, clinical oversight is crucial to ensure balanced dosing and to avoid overstimulation of growth pathways

The activity of GLS and GDH is higher in activated than resting T cells in the mouse spleen, which can be blocked by inhibiting the ERK signal pathway, the downstream of TCR/CD28 signaling (53)

A multicentre randomized double-blind placebo-controlled phase III study of the efficacy and safety of xeligekimab (GR1501) in patients with moderate-to-severe plaque psoriasis

Along the same line, depleting endogenous GSH with BSO had a worsening effect in some of the models above, including chemically induced pulmonary edema, 21 cigarette smoke, 31 carrageenan-induced pleurisy, 32 and endotoxin-induced pulmonary inflammation

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