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Iron and 4HNE levels in the spleen and liver tissues are stained with Prussian blue staining (#IW-3010, IHC world) and immunohistochemistry (IHC) staining

Arpaia N, Green JA, Moltedo B, Arvey A, Hemmers S, Yuan S, et al

Protein concentration was determined using a BCA kit (Thermo Scientific), after which samples were diluted to 1 mg ml 1 in 5% SDS and 50 mM TEAB

Collectively, these data suggested the limited activity of CB-839 monotherapy in CLL cell lines

In OA, chronic low-grade inflammation can lead to further degeneration of joint cartilage, sclerosis of subchondral bone, and the formation of osteophytes, thereby aggravating joint damage and pain [14]

UV rays can exacerbate dark spots, so daily application of a broad-spectrum sunscreen is essential