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Stopping Criteria require all of the following : [1] Acetaminophen level is 25-50% from peak value

At 36 and 40 h, in mid-late G1 phase, the hepatic mRNA levels of Hgf appeared significantly lower in Gstp1/2 / along with a limited induction of Cyclin D1 mRNA levels at 40 h compared with their strong increase in the WT livers (Figure 5d)