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For research examining multiple pathways, a blend approach may be more appropriate

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In ageing yeast, spermidine treatment triggered the deacetylation of the histone, H3, through the inhibition of histone acetyltransferases (HAT EC 2.3.1.48), suppressing oxidative stress and inducing apoptosis [115]

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PLoS ONE 8:e66830

G.HuntleyJ.AmesD.et al