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Yen K, Wan J, Mehta HH et al (2018) Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans

In addition, a small pilot safety study published in Alternative Therapies in Health and Medicine showed that intravenous infusions of BPC-157 up to 20 milligrams were well-tolerated with no reported adverse effects in healthy adults, providing initial evidence that the peptide can be administered safely, a necessary step before larger efficacy trials on healing outcomes are conducted

doi:10.1016/S0021-9258(18)55367-9

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BPC 157 accelerates the reconstruction of microvessels in damaged tissues by activating the VEGF pathway, thereby improving local blood circulation and accelerating the healing speed

4 Inflammasome-mediated liver injury: DAMPs released from stressed hepatocytes, damaged mitochondria, and necrotic liver cells activate inflammasome sensors, triggering the oligomerization and activation of inflammasome components