Also known as somatomedin C, it is a peptide hormone synthesized in the liver as the principal downstream mediator of growth hormone activity
And it's especially evident when he talks about how improving his gut health may benefit his family
J Mol Endocrinol 25 , 141148 (2000)
Representative data of 34 experiments (n = 5, two-sided unpaired t-test)
Mechanically, pre-clinical evidence highlights VNS as a multifaceted therapy for IBS, including reducing inflammation via 7 nicotinic acetylcholine receptor-mediated suppression of TNF-, alleviating visceral hypersensitivity, increasing colorectal distension thresholds, enhancing motility through M3 receptor activation and gastric emptying, restoring gut microbiota diversity via elevating bifidobacterium abundance and short-chain fatty acids, and improving intestinal barrier integrity
Some experimental findings suggest that GHRP-6 may compete with oxidized lipoproteins for receptor binding, which could alter foam cell development in atherosclerosis models