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Among them, GPX4 is a membrane-associated phospholipid hydroperoxidase, and it is also the only enzyme in the GPX family that directly reduces and destroys lipid hydroperoxides, which can reduce complex lipid compounds in addition to reducing H 2 O 2 and small molecule hydroperoxides

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It is also used to manage post-traumatic brain injuries, jet lag, neurodegenerative disorders, and migraines

Caspase-3 is known to be activated by ROS [54, 78] and promote PS externalization in eryptosis [135, 136]