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From this screening, seven drugs that showed activity consistently on three or more separate occasions were chosen for further analysis

The randomization to sequences was stratified by sex and performed dynamically by the minimization technique using the dynamic allocation algorithm, second-best probability set to 15%, with the help of the Medidata-RTSM software

The increased PEP also inhibited phosphofructose kinase (encoding by pfk ) activity, which was responsible for the decreased glycolytic flux and the down regulation of the glycolytic activities [33]

doi: 10.3390/medicina61020254

PMID: 19280591

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