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Mitochondria are central to the regulation of apoptosis, with Cyt C functioning as a key pro-apoptotic molecule

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VRK2 overexpression induced an increase in the expression of SLC7A11 at the PM level but not at the whole cell level

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CSCs are a subpopulation of tumor cells with the capability to self-renew and differentiate, which drives tumor progression and metastasis

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41 Notably, SIRT1 also plays a crucial role in regulating mitochondrial bio-oxidation synthesis in a PGC-1 dependent manner

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