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When p53 transcriptional activity in response to 5-FU treatment was measured, the mRNA and protein levels of p21, which is a p53 target gene, were decreased in the GST WT -p53-expressing cells

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[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Agathos E., Tentolouris A., Eleftheriadou I., Katsaouni P., Nemtzas I., Petrou A., Papanikolaou C., Tentolouris N

NAC altered doxorubicin-induced NF-B activity via concentration-dependent anti- and pro-oxidant mechanisms (27)