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(2019) HCG-Mediated Immune Responses That Facilitate Embryo Implantation and Placentation Front Immunol 10:2896

Toxicology research indicates the peptide has no lethal dose in rat models even at extremely high concentrations, and chronic administration studies show no organ toxicity or significant biochemical abnormalities

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Because it does not suppress appetite, it can theoretically be combined with GLP-1 agonists to add a lipolytic component to the appetite suppression mechanism, though clinical data on this combination is lacking