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BBR is mostly associated with mild gastrointestinal discomfort at high doses (Prajwala et al

Clin Chem 39 : 980985

As a result, critical information regarding the exact compounds used, dosages, duration of exposure, cycling patterns, and the concurrent use of additional substances in multi-drug regimenswhether intentional or unintentionaloften relies on retrospective self-reporting by users, which is inherently subject to recall bias and misclassification

Pre-clinical studies have reported that these molecules quench reactive oxygen species (ROS), upregulate epidermal growth factor (EGF) signaling, and suppress matrix metalloproteinases (MMPs), thereby protecting fibroblasts and keratinocytes from ultraviolet (UV) stress and senescence

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