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We identified eight DEGs in the ferroptosis signaling pathway (Fig

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Schwalfenberg, 2021), sex, low intracellular GSH, cigarette smoking and presence of chronic diseases, among other factors, and GSH deficiency caused by any or all these factors may contribute to severe COVID-19 disease pathogenesis (Polonikov, 2020

50,51 Recent metabonomics retrospective studies had shown that increased plasma levels of BCAAs are associated with an increased risk of pancreatic cancer, which was validated in a genetically engineered mouse model of pancreatic ductal adenocarcinoma (PDAC)

However, one common factor crops up in many sleep-deprived people oxidative stress