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The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease

A novel microfluidic device-based neurite outgrowth inhibition assay reveals the neurite outgrowth-promoting activity of tropomyosin Tpm3.1 in hippocampal neurons

The analysis aimed to estimate (1) breed-type differences at baseline (SG-NE vs FG-NE), (2) within-breed responses to the enrichment factor (SG-E vs SG-NE, FG-NE vs FG-E) and (3) between-breed responses to the enrichment factor (breed-type-specific responses)

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In this study, MM/PBSA is used to calculate the binding free energy between tyrosinase (hTYR and mTYR) and inhibitors, in order to assess the strength of their interactions and screen potential binding modes with high affinity 59