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Regulation of FoxO activity by CBP/p300-mediated acetylation

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At the same time, transcription of the gene encoding fatty acid synthase, a multi-enzyme protein that catalyzes the synthesis of fatty acids, increases because ChREBP becomes active due to the removal of its inactivating phosphate group

Constant aerobic cycling training did not exceed 75% maximum heart rate or maximum oxygen consumption, while diet and supplement protocols were also held constant throughout the test period