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For instance, in hepatocellular carcinoma HepG2 cells, CGA was able to prevent the degradation of the extracellular matrix by reducing the expression of MMP-2 and MMP-9, thus inhibiting the migration and invasion of tumor cells [82]

Another randomized controlled trial in men with biochemically relapsing cancer after radical prostatectomy suggested that prostate-specific antigen (PSA) values tended to increase less in those given daily oral sulforaphane (4.4 or 26.6 mg/day) for six months compared to those receiving the placebo (61)

Five children required mechanical ventilation, and two died (73)

RAGE is a transmembrane receptor and is expressed in numerous tissues including ovaries, heart, lung and skeletal muscle, but also in monocytes, macrophages and lymphocytes [41]