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Impact of select actionable genomic alterations on efficacy of neoadjuvant immunotherapy in resectable non-small cell lung cancer

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Funding The authors acknowledge that the funding obtained from the Research, Development, and Innovation Authority (RDIA), Saudi Arabia, Riyadh, Reactivating & Rebuilding of Existing Labs Initiative, Number (13262-Tabuk-2023-UT-R-31-HW-), supporting the generation of these data and publication)

The increased expression of SAT1 promotes the depletion of spermidine and spermine, which leads to mitochondria-mediated apoptosis, and increases the sensitivity of drug-resistant cells to cisplatin-induced apoptosis (Mandal et al., 2015)

When you book an appointment online, you will complete a short medical questionnaire, which our nurse prescriber will review

Lorca, G