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In addition to the copper-induced accumulation of lipoylated mitochondrial DLAT enzymes, there is also a loss of ironsulfur (Fe-S) cluster proteins, leading to proteotoxic stress [21,39,40,41]

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Of 11 patients with a history of gastrectomy, 10 patients underwent gastrectomy due to gastric cancer and 1 patient due to abdominal rupture caused by a traffic accident

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G.CassA.et al (2020)