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Key points for patients: GLP-1 therapies help clear skin and reduce painful, swollen joints Obesity makes PsA harder to treat, so weight loss from GLP-1 meds helps In studies, patients on GLP-1s had fewer flares, less pain, and felt better overall

Jul 2020;38(3):308-322

GLP-1 peptide Cagrilintide alone has similar effects, but they happen through different receptor pathways

Also, Gromadzka et al., did not note the impact of the tested genotypes on the risk of developing neuropsychiatric symptoms of WD, but a significant impact of the IL1RN *2 allele on the age of patients at the time of occurrence of these symptoms was observed [111]

MBOAT1 and MBOAT2 remodel PLs to protect cells from ferroptosis independent of GPX4

However, peptides sold for research purposes are not approved for human use