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It affects your brain by acting like a neurotransmitter called acetylcholine and by boosting other neurotransmitters like dopamine, which makes you feel good by flooding the rewards system in your brain

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Nicotine is highly addictive and can raise your blood pressure and spike your adrenaline, which increases your heart rate and the likelihood of having a heart attack

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[1] The IARC monographs conclude that mice with prolonged exposure to simulated second-hand smoke, that is six hours a day, five days a week, for five months with a subsequent four-month interval before dissection, will have significantly higher inicidence and multiplicity of lung tumors than with control groups