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48 (shiny.cnsgenomics.com/mRnd/) and the R 2 previously calculated, in which the power to detect an effect of OR 0.8 on PD risk in the iPDGC dataset with an alpha of 5% was evaluated for each trait (see Table 1)

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17 Structured programs with regular review of progress facilitate achievement of weight loss and appear essential, as demonstrated by inability to reduce AF burden in a small RCT that achieved only 4.5% weight loss in the intervention arm