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13, 54 Our mechanistic investigations demonstrated that BSO+L-PAM induced significant increases in mitochondrial depolarization, cleavage of caspase-3, caspase-9, poly ADP ribose polymerase and DNA fragmentation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Liberati A., Altman D.G., Tetzlaff J., Mulrow C., Gtzsche P.C., Ioannidis J.P.A., Clarke M., Devereaux P.J., Kleijnen J., Moher D

Due to its limited oral bioavailability in humans (see Metabolism and Bioavailability), plasma and tissue curcumin concentrations are likely to be much lower than those of other fat-soluble antioxidants like -tocopherol (vitamin E)

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