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Atrophy of the right hippocampus and temporal lobes (Serra et al., 2010), reduced cortical thickness of the left medial orbitofrontal region (Whitehead et al., 2012), and hypometabolism of the left occipital region (Serra et al., 2010)

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Journal of Obstetrics and Gynaecology Research 47(5):18171824 Black S, Romn GC, Geldmacher DS, Salloway S, Hecker J, Burns A, Perdomo C, Kumar D, Pratt R (2003) Efficacy and tolerability of donepezil in vascular dementia: positive results of a 24-week, multicenter, international, randomized, placebo-controlled clinical trial

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For example, high levels have been linked with obesity and obesity-related illnesses such as diabetes, renal failure, and liver disease

However, both peptides contribute to the inflammatory milieu that accelerates immune ageing