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Gut Health: Both Semaglutide and BPC-157 have beneficial effects on gut health, including improving digestion, reducing gut inflammation, and enhancing the integrity of the gastrointestinal mucosa

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults, [19.06.2025] 4

(PubMed) Marti-Carvajal AJ, Sola I, Lathyris D, Dayer M

This means no TUE pathway exists for BPC-157

Other at-risk groups include people with coeliac or Crohns disease, those who have had weight loss surgery, and those with atrophic gastritis or pernicious anaemia

The combined GLP-1/GIP profile is what gives tirzepatide its edge over semaglutide