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To eliminate the potential impact of light exposure, three independent preparations of Nano-Lut and Nano-Bc were assessed fresh (at the zero-time interval) and then stored in opaque glass vials

Unlike peptides, this compound is not composed of amino acid chains and is produced via chemical synthesis rather than peptide assembly

Especially, benzylidene-2-thiohydantoins and 5-benzylidene(thio)barbiturates showed greater inhibitory potency (Figure 7)

However, there were no significant changes in membrane proteins in either cell line after metformin treatment (Supplementary Fig

10.1093/humupd/dmx033 43 CuiX.LiuX.FengH.ZhaoS.GaoH