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Higher doses are used clinically for acetaminophen overdose and severe oxidative stress, but for daily glutathione optimisation, 6001,200 mg is sufficient once the glycine substrate is in place

The formulation or composition is designed to provide drug delivery over a desired period of time, including periods up to several weeks

Intracellular redox balance is primarily due to cyclic oxidation and reduction of glutathione both in the mitochondria and cytoplasm of the cells

Together, researchers combine them to examine potential complementary mechanisms in preclinical model systems