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Metabolic reprogramming and altered cell envelope characteristics in a pentose phosphate pathway mutant increases MRSA resistance to -lactam antibiotics

Cell 138 : 114128

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Moreover, the UA transportersURAT1, GLUT9, and ABCG2play crucial roles in regulating UA levels, with dysfunctional transporters leading to abnormal serum UA levels, as observed in hypouricemia and hyperuricemia

Researchers supporting the inverse association between smoking and hyperuricemia suggest that this mechanism may be responsible for their results 2,9