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Potent anti-neutrophil agent with cardioprotective effects [1
Retinol binding protein 4 (RBP4
type I nodal receptor ALK4 and type I nodal receptor ALK7
The Kis are 16 pM and 30 pM for Src and Bcr-Abl
AG-CN2-0020) for 30 min
Forskolin Pack Size:200 mg Potent anti-neutrophil agent with cardioprotectiveForskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0. 5 M for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.
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