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We defined two sets of genes, those either largely devoid of promoter bound NRF2 (Group I, green) or genes with high promoter bound NRF2 (Group II, purple) (Fig

In some cases, both second messenger-dependent protein kinases and GRKs are able to phosphorylate and desensitize the same GPCR (Figure 1c) (for example, Hausdorff et al ., 1989

When it breaks down, trouble begins [19]

FENIX assay Egg PC liposomes (extruded to 100 nm, 1 mM), STY-BODIPY (1 M), and cholesterol (40 M), desmosterol (40 M), 7-DHC (40 M), or vehicle (MCD) were vortexed in PBS (10 mM, 150 mM NaCl, pH7.4), then 200 l aliquots were incubated in a black 96-well plates (polypropylene, Nunc) for 20 min at 37 C