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Vitamin B12, also known as cobalamin, plays a key role in maintaining essential body functions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.De Rosa S.C., Zaretsky M.D., Dubs J.G., Roederer M., Anderson M., Green A., Mitra D., Watanabe N., Nakamura H., Tjioe I., et al

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This is why prescribers routinely instruct patients to take isotretinoin with food [1]

Nature 582(7811):289293