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SB increases the fraction of cells in the G1 phase of the cell cycle and was suggested to exhibit its antiproliferative action via blocking the transition of the cell cycle from the G1 phase to the S phase or by arresting the cell cycle at the G1 phase (Lee et al., 2004d)

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Retatrutide is a synthetic peptide based on a glucose-dependent insulinotropic polypeptide (GIP) backbone, but uniquely, it functions as a triple agonist