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Tail vein (165, 166), hepatic vein (167) and peripheral vein (168) injection of MSCs in an ischaemia-reperfusion injury animal model showed that MSC infusion can reduce liver damage and cell death (165, 167), improve the levels of ALT and AST (166168) and mainly decrease oxidative stress caused by liver excision and ischaemia-reperfusion injury (169)

Seventy patients were eligible for the study, based on the above criteria

The limit of 100 conformers was chosen as this is considered to be a standard number of conformers to be used in molecular modelling analyses and to balance computational time requirements whilst ensuring the production of an appropriate ensemble size [29]