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We expect in the near future growing recognition of GSH involvement, by S -glutathionylation and/or by the thiols redox state shift, not only in the induction of ATG and/or apoptosis, but also in the modulation of activities of molecular/transcription factors such as NEF2L2, PGC1, and p53 that by inducing the antioxidant defense and assuring mitochondrial homeostasis could block both processes
Barkhordari, A., Mahnam, K., & Mirmohammad-Sadeghi, H
Each time a cell divides, its telomeres shorten, accelerating the aging process
In lupus-prone females, reduced abundance of Erysipelotrichaceae and Bifidobacterium, with increased Lachnospiraceae and Bacteroidetes S247 abundance, has also been reported ( These findings suggest that microbiological dysbioses specific to sex, more precisely the increased prevalence of Lachnospiraceae in females, may account for the earlier onset and greater severity of lupus symptoms
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