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It also plays a major role in glutathione's antioxidant and detoxification functions

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FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012

Protein oxidation and cellular homeostasis: Emphasis on metabolism

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