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doi: 10.1038/s41467-022-34399-y, 27 EnersonB

refers to DNA methylation in the promoter region of GSTP1 gene responsible for epigenetic silencing of this isoenzyme

The integrated metabolism-immune-neuro interaction model presented in this article may provide a potential comprehensive framework for understanding PEM and highlights the need for a multi-target, collaborative intervention approach that may help disrupt the pathological cycle

Wang W, Liu H, Wang F, Liu X, Sun Y, Zhao J, et al

Research-only escalation preview This preview illustrates how study participants were escalated from lower starting doses up to their final weekly dose