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Thus, inflammasome regulation in wound healing is a dynamic interplay between host molecular sensors and microbial signals, where temporal control combined with a balanced microbiome determines whether wounds progress toward regeneration or chronic inflammation

Nat Med (2017) 23(1):1207

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When there are unusually high levels of T3 and T4, this essentially sends a message to the brain to reduce the production of TSH to help all thyroid hormones stay within their optimal ranges