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In patients with DM, central nervous system dysfunction related to hyperglycemia is common ( Although various factors, including chronic hyperglycemic stimuli, repeated episodic hypoglycemia and ketoacidosis, damage to the BBB, insulin dysfunction in the brain, cardiovascular risk factors, and metabolic changes, have been explored, the pathogenesis of diabetes-related cognitive impairment is still a subject of preliminary investigation

Multiply daily dose by days per week by number of weeks

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Older Patients Older patients should take CB-12 Injection under medical supervision as they may be more susceptible to its side effects

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doi: 10.1172/JCI40034 160 YangJJPendergraftWFAlcortaDANachmanPHHoganSLThomasRPet al